Potassium Tert-Butoxide(KTB)

Potassium tert-butoxide (KTB) is a white crystalline powder, hygroscopic, decomposes in water, and is soluble in organic solvents. As a strong basic catalyst, it is primarily used in organic synthesis, pharmaceutical intermediate preparation, and chemical reaction catalysis. It must be stored in a sealed, dry place, away from water and acidic substances, and handled with care to prevent moisture absorption.
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Product Parameters

Index NameIndexPacking standard
Total alkali≥99%

Galvanized steel drum:100kg

Cardboard drum:25kg

Free alkali≤1%
Appearancewhite powder
CAS No.865-47-4
Molecular formulaC4H₉OK
Molecular weight112.22



Basic Properties

  • Appearance: Usually a white or off-white powder, sometimes pale yellow depending on purity.

  • Basicity: As a strong base (pKa of t-BuOH ~ 17), it is ideal for deprotonating weakly acidic C-H bonds.

  • Solubility: Soluble in tert-butanol itself and exhibits good solubility in common organic solvents such as tetrahydrofuran (THF), dimethyl sulfoxide (DMSO), and dimethylformamide (DMF). It reacts violently in water.

  • Hygroscopicity and Reactivity: KTB is extremely hygroscopic, rapidly absorbing moisture and carbon dioxide from the air, decomposing into potassium hydroxide and potassium carbonate, thus leading to its degradation. Therefore, it must be stored and handled under strict sealing conditions under an inert gas atmosphere (such as nitrogen or argon).

  • Steric Hinderment: Its large tert-butyl group creates a significant steric hindrance effect. This not only affects its nucleophilicity but also makes it prone to forming thermodynamically more stable alkenes in elimination reactions (following Hoffmann's rule).

Main Applications

  • Synthesis of key intermediates in the pharmaceutical industry

  • Strongly basic reagents in organic synthesis

  • Polymerization catalysts

  • Semiconductor and electronics industries

Safety Precautions

  • Hazards: KTB is highly corrosive and irritating to skin, eyes, and respiratory tract. It reacts violently with water, releasing heat and potentially causing combustion.

  • Handling: Must be performed in a well-ventilated environment (e.g., a fume hood) while wearing appropriate personal protective equipment, such as goggles, corrosion-resistant gloves, and a lab coat.

  • Storage: Always store in a dry, inert atmosphere (nitrogen purging), sealed away from moisture, water, and acids.

Company Profile

Junteng Chemical is a professional chemical raw materials trading company dedicated to providing customers with one-stop procurement services. Through strict supplier, supply chain, and after-sales management, the company ensures that product quality, transportation, and use meet customer needs. Furthermore, the company's technical team offers customized solutions and support services free of charge.

 

The company has projects in the pharmaceutical, pesticide, petrochemical, construction, food additives, wastewater treatment, adhesives, inks, paints, coatings, plastic and rubber processing, detergent raw materials, fertilizer and textile mills, and more. Junteng Chemical sources products of stable and reliable quality, collaborating with domestic and international companies such as Luxi Group, Weiyuan Chemical, Qilu Petrochemical, Dongying Lihuayi, Yanshan Petrochemical, Sinopec, Shijiazhuang Refinery, Qingdao Petrochemical, Sailboat, Dow Chemical, BASF, South Korea, Taiwan, and Saudi Arabia. Our stable supply, superior product quality, and mature logistics have earned us a wide clientele. We look forward to collaborating with all of you for a mutually beneficial future.

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Company advantages

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One-Stop Procurement
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Equipped with an experienced technicalteam, we provide free personalizedsolutions and professional technicalsupport to customers in varlous industrie,such as pharmaceuticals, petrochemicals,coatings and inks, and sewage treatment,.helping you solve problems and improveefficiency.

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