Di-Tert-Butyl Dicarbonate(DIBOC)

Di-Tert-Butyl Dicarbonate (DIBOC, CAS 24424-99-5) is a key amine-protecting reagent, ideal for peptide synthesis, organic synthesis—high purity, reliable performance.
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Product Parameters

Index NameIndexPacking standard
Content≥99%Galvanized steel drum:50/180kg
Molecular formulaC10H18O5
Molecular weight218.25
Appearancewhite transparent liquid or crystal
CAS No.24424-99-5

Basic Properties

Physical Properties

  • Appearance: White to pale yellow crystals or powder

  • Melting Point: 22-24°C

  • Boiling Point: 56-57°C (0.5 mmHg)

  • Density: 1.02 g/cm³ (20°C)

  • Solubility: Easily soluble in organic solvents (such as dichloromethane, THF, acetonitrile), slightly soluble in water

  • Molecular Weight: 218.25 g/mol


Chemical Properties

  • Stability: Sensitive to moisture; requires dry storage

  • Reactivity: Serves as a source of tert-butyloxycarbonyl (Boc) protecting groups

  • Decomposition Temperature: Decomposes at approximately 150°C

  • Storage Conditions: Refrigerate at 2-8°C under inert gas protection


Main Applications

1. Pharmaceutical Intermediate Synthesis

  • Amino Acid Protection: Widely used for amino acid protection, especially in peptide synthesis.

  • Antibiotic Production: Serves as a key intermediate in the synthesis of many antibiotics.

  • Active Pharmaceutical Ingredients (APIs): Used in the synthetic routes of various drugs.


2. Peptide Synthesis

  • Boc Protection Strategy: Protects amino groups in solid-phase peptide synthesis.

  • Selective Protection: Enables selective protection and deprotection of amino groups.


3. Organic Synthesis

  • Amino Protecting Reagents: Used for the protection of amine compounds.

  • Functional Group Transformation: Participates in the introduction and transformation of various functional groups.

  • Asymmetric Synthesis: Used as a protecting group in chiral synthesis.


4. Other Applications

  • Materials Science: Used for the preparation of functionalized materials.

  • Biochemistry: Research on protein and enzyme modification.

Safety Precautions


Storage and Handling

  • Storage Conditions: Store in a sealed container at 2-8°C in a dry environment, protected with an inert gas atmosphere.

  • Humidity Control: Keep the environment dry and avoid contact with moisture.

  • Compatibility: Avoid contact with strong oxidizers, strong acids, and strong alkalis.


Safety Precautions

  • Personal Protection:

  • Wear chemical safety goggles.

  • Wear chemical protective gloves (nitrile or neoprene).

  • Operate in a well-ventilated area.

  • Use a face shield if necessary.

  • Handling Precautions:

  • Avoid inhaling dust or vapors.

  • Prevent skin and eye contact.

  • Use explosion-proof equipment.

Company Profile

Junteng Chemical is a professional chemical raw materials trading company dedicated to providing customers with one-stop procurement services. Through strict supplier, supply chain, and after-sales management, the company ensures that product quality, transportation, and use meet customer needs. Furthermore, the company's technical team offers customized solutions and support services free of charge.

 

The company has projects in the pharmaceutical, pesticide, petrochemical, construction, food additives, wastewater treatment, adhesives, inks, paints, coatings, plastic and rubber processing, detergent raw materials, fertilizer and textile mills, and more. Junteng Chemical sources products of stable and reliable quality, collaborating with domestic and international companies such as Luxi Group, Weiyuan Chemical, Qilu Petrochemical, Dongying Lihuayi, Yanshan Petrochemical, Sinopec, Shijiazhuang Refinery, Qingdao Petrochemical, Sailboat, Dow Chemical, BASF, South Korea, Taiwan, and Saudi Arabia. Our stable supply, superior product quality, and mature logistics have earned us a wide clientele. We look forward to collaborating with all of you for a mutually beneficial future.

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Company advantages

1

One-Stop Procurement
Platform

We integrate resources across all productcategories, including organic solvents,resins and rubbers, and inorganicchemicals,and strictly control suppliers.supply chains, and after-sales processes toensure stable quality, efficienttransportation,and worry-free use,simplifying your procurement process.

2

Professional Team TechnicalEmpowerment

Equipped with an experienced technicalteam, we provide free personalizedsolutions and professional technicalsupport to customers in varlous industrie,such as pharmaceuticals, petrochemicals,coatings and inks, and sewage treatment,.helping you solve problems and improveefficiency.

3

Global supply ChainSecurity

We work with top domestic and foreignchemical giants such as Luxi Group, QiluPetrochemical, Sinopec, BASF of Germany,and Dow of the United States to establisha stable and reliable high-quality supplynetwork and a mature logistics system toensure timely and safe delivery of
products.

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Deep Win-Win CooperationConcept

Adhering to the concept of "integrity.immediate action, professionalism,innovation and win-win" and taking"customer success and altruism" as ourmission, we are committed to establishinglong-term strategic partnerships andcreating a better future through excellentproducts and services.

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