2-Chlorophenylacetonitrile

O-Chlorophenylacetonitrile, molecular formula C₈H₆ClN, molecular weight 151.59, is a colorless to pale yellow transparent liquid at room temperature (prone to solidification at low temperatures) with a mildly pungent odor. It has a boiling point of 246–248°C and is readily soluble in organic solvents such as ethanol and diethyl ether, while slightly soluble in water.
Its molecule contains a reactive cyano group and a chlorine atom, making it a key intermediate in synthesizing pharmaceuticals, pesticides, and dyes. It is widely used in the production of antifungal drugs, herbicides, and other products. Complete quality inspection reports are provided, with a dedicated technical support team available 24/7 for inquiries.
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Product Parameters

ITEMSSPECIFICATION
AppearanceColorless or yellowish oily liquid
Content (%)99min
Water(%)0.3 max

Basic Properties


1. Physical Properties

  • Appearance: Colorless to pale yellow transparent liquid (or crystalline solid, prone to solidification at low temperatures), with a mildly pungent odor.

  • Molecular formula: C₈H₆ClN, molecular weight: 151.59, Boiling point 246-248°C, melting point 31-33°C, density 1.18 g/cm³ (20°C).

  • Solubility: Easily soluble in organic solvents such as ethanol, diethyl ether, and chloroform; slightly soluble in water; miscible with most organic reagents.

2. Chemical Properties

  • Its molecular structure contains reactive cyano (-CN) and chlorine (-Cl) atoms, making it prone to hydrolysis, reduction, and substitution reactions. For instance, the cyano group may hydrolyze to a carboxyl group, while the chlorine atom can be substituted by amino or hydroxyl groups.

  • Reactions accelerate upon contact with strong acids or bases. Decomposition at elevated temperatures may release toxic gases, necessitating strict control of reaction conditions. 3. Stability

  • Stable when stored sealed at room temperature. Avoid co-storage with strong oxidizing agents, strong acids, or strong bases to prevent chemical reactions.

  • Possesses moderate volatility and readily absorbs moisture when exposed to air over extended periods. Store in a sealed container to prevent moisture absorption, and keep away from fire sources and high-temperature environments.

Main Applications


1. Pharmaceutical Sector

Serves as a core intermediate in synthesizing antipsychotic and antihistamine drugs, such as intermediates for schizophrenia treatments. Through reactions like cyanohydrin hydrolysis and reduction, it constructs key structural units within drug molecules, ensuring therapeutic efficacy and safety. It also facilitates the synthesis of antibacterial drugs, aiding in anti-infective drug development.

2. Pesticide Industry

Primarily used to produce highly effective, low-toxicity herbicides and insecticides. For instance, it synthesizes selective herbicides targeting broadleaf weeds by inhibiting key enzyme activity within weeds, achieving weed control while maintaining high safety for crops. It also serves as an insecticide intermediate, enhancing pesticide targeting against pests and reducing environmental residues.

3. Fine Chemicals Sector

Used in preparing specialty dyes and fragrances. In dye synthesis, it introduces functional groups via substitution reactions to improve color stability and adhesion. In the fragrance sector, it serves as a raw material for synthesizing aromatic compounds, imparting unique olfactory layers to fragrances and finding applications in cosmetic fragrance production.

Safety Precautions


1. Safety Precautions

  • Wear a respirator, chemical-resistant gloves, and safety goggles during operation. Avoid inhaling vapors or allowing liquid contact with skin or mucous membranes to prevent burns or allergic reactions.

  • Operate within a fume hood. Never work near open flames to prevent vapor ignition. Avoid mixing with strong oxidizing agents, strong acids, or strong alkalis to prevent violent reactions.

  • After use, promptly wash hands and clothing. Maintain ventilation in the work area. Do not eat, drink, or consume beverages in the operational zone.

2. Storage Safety

  • Store in sealed containers within a cool, dry, well-ventilated, explosion-proof warehouse. Maintain temperatures below 30°C. Keep away from fire sources, heat sources, and oxidizing agents. Store separately to prevent cross-contamination.

  • Use corrosion-resistant packaging clearly labeled with “Toxic Chemical” and “Moisture/Fire Prevention” warnings. Strictly prohibit access by children or non-operators.

3. Emergency Response

  • If vapors are inhaled, immediately move to fresh air, maintain airway patency, and seek medical attention promptly if breathing difficulties occur. For skin or eye contact, flush with copious amounts of running water for 20 minutes before seeking medical care.

  • In case of leakage, immediately isolate the contaminated area. Absorb spills with sand or absorbent material and dispose of as hazardous waste according to regulations. Direct discharge into the environment is strictly prohibited.

Company Profile

Junteng Chemical is a professional chemical raw materials trading company dedicated to providing customers with one-stop procurement services. Through strict supplier, supply chain, and after-sales management, the company ensures that product quality, transportation, and use meet customer needs. Furthermore, the company's technical team offers customized solutions and support services free of charge.

 

The company has projects in the pharmaceutical, pesticide, petrochemical, construction, food additives, wastewater treatment, adhesives, inks, paints, coatings, plastic and rubber processing, detergent raw materials, fertilizer and textile mills, and more. Junteng Chemical sources products of stable and reliable quality, collaborating with domestic and international companies such as Luxi Group, Weiyuan Chemical, Qilu Petrochemical, Dongying Lihuayi, Yanshan Petrochemical, Sinopec, Shijiazhuang Refinery, Qingdao Petrochemical, Sailboat, Dow Chemical, BASF, South Korea, Taiwan, and Saudi Arabia. Our stable supply, superior product quality, and mature logistics have earned us a wide clientele. We look forward to collaborating with all of you for a mutually beneficial future.

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Company advantages

1

One-Stop Procurement
Platform

We integrate resources across all productcategories, including organic solvents,resins and rubbers, and inorganicchemicals,and strictly control suppliers.supply chains, and after-sales processes toensure stable quality, efficienttransportation,and worry-free use,simplifying your procurement process.

2

Professional Team TechnicalEmpowerment

Equipped with an experienced technicalteam, we provide free personalizedsolutions and professional technicalsupport to customers in varlous industrie,such as pharmaceuticals, petrochemicals,coatings and inks, and sewage treatment,.helping you solve problems and improveefficiency.

3

Global supply ChainSecurity

We work with top domestic and foreignchemical giants such as Luxi Group, QiluPetrochemical, Sinopec, BASF of Germany,and Dow of the United States to establisha stable and reliable high-quality supplynetwork and a mature logistics system toensure timely and safe delivery of
products.

4

Deep Win-Win CooperationConcept

Adhering to the concept of "integrity.immediate action, professionalism,innovation and win-win" and taking"customer success and altruism" as ourmission, we are committed to establishinglong-term strategic partnerships andcreating a better future through excellentproducts and services.

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